您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > Bismuth Subsalicylate
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Bismuth Subsalicylate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bismuth Subsalicylate图片
CAS NO:14882-18-9
包装与价格：
包装价格(元)
500mg电议
5 g电议
10 g电议

产品介绍
Bismuth Subsalicylate 是一种有效的、具有口服活性的抗酸剂和止泻剂。
Cas No.14882-18-9
别名次水杨酸铋; Bismuth oxysalicylate; Bismuth(III) salicylate basic
化学名1,3,2λ2-benzodioxabismin-4-one;hydrate
Canonical SMILESC1=CC=C2C(=C1)C(=O)O[Bi]O2.O
分子式C7H5BiO4
分子量362.09
溶解度<3.62mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.Target: OthersBismuth Subsalicylate reduces inflammation/irritation of stomach and intestinal lining through inhibition of prostaglandin G/H Synthase 1/2 [1]. Bismuth Subsalicylate is the active ingredient in Pepto-Bismol, an anti-diarrhea medication and antacid. In the gastrointestinal tract, Bismuth Subsalicylate is converted to salicylic acid and insoluble bismuth salts [2]. Bismuth subsalicylate treatment for 8 weeks is safe and well tolerated. This regimen appears to be efficacious for the treatment of microscopic colitis and is worthy of further study in a controlled trial [3].

References:
[1]. Sox, T.E. and C.A. Olson, Binding and killing of bacteria by bismuth subsalicylate. Antimicrob Agents Chemother, 1989. 33(12): p. 2075-82.
[2]. Bierer, D.W., Bismuth subsalicylate: history, chemistry, and safety. Rev Infect Dis, 1990. 12 Suppl 1: p. S3-8.
[3]. Fine, K.D. and E.L. Lee, Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis. Gastroenterology, 1998. 114(1): p. 29-36.