CAS NO: | 114-80-7 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
100mg | 电议 |
500mg | 电议 |
Cas No. | 114-80-7 |
别名 | 溴化新斯的明; Eustigmin bromide; Neoserine bromide |
化学名 | [3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium;bromide |
Canonical SMILES | CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-] |
分子式 | C12H19N2O2.Br |
分子量 | 303.2 |
溶解度 | ≥ 15.16mg/mL in Water |
储存条件 | Store at -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Neostigmine bromide is a reversible inhibitor of acetylcholinesterase.[1] AChE (acetylcholinesterase) is a hydrolase that hydrolyzes the neurotransmitter acetylcholine at the neuromuscular junction and cholinergic synaspe. It terminates the signal transductions and plays a role in neuronal apoptosis. Neostigmine bromide is a quaternary amine that blocked cholinesterase activity to extend and enhance the muscarinic and nicotinic effects of acetylcholine. It is implicated for the treatment of primary open-angle glaucoma, postoperative urinary retention, paralytic ileus, myasthenia gravis etc. It is also reported to be an adjuvant to local anaesthetics and opioids for post-surgical pain after gynaecological or abdominal surgery. [1] Reference: |