Lumiracoxib 是一种有效的、选择性的、具有口服活性的 COX-2 抑制剂,其 Ki 值为 0.06 μM。
Cas No. | 220991-20-8 |
别名 | 罗美昔布; COX-189 |
化学名 | 2-[2-(2-chloro-6-fluoroanilino)-5-methylphenyl]acetic acid |
Canonical SMILES | CC1=CC(=C(C=C1)NC2=C(C=CC=C2Cl)F)CC(=O)O |
分子式 | C15H13ClFNO2 |
分子量 | 293.72 |
溶解度 | ≥ 29.4mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Kiof 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4. |