CL218872 是口服有活性的苯二氮卓类选择性激动剂，激动含有 α1 亚基的GABAA受体(Ki:130 nM)。它在体内具有抗惊厥及抗焦虑效果。

CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, >10000, 490 and >10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo.

66548-69-4

C13H9F3N4

278.238

DMSO:13.9 mg/mL (50 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years