Adrenomedullin (AM) (22-52), human acetate 是猫后肢血管床中 CGRP 受体和肾上腺髓质素受体的拮抗剂。
产品描述
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an adrenomedullin receptor.
体外活性
Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base) competitively inhibits the binding of the Adrenomedullin dose-dependently and inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells. Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base) (30 nmol) selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) with similar effect to that of CGRP antagonist[1].
分子式
C161H256N46O50
分子量
3636.09
别名
Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years