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Boc-NH-C4-Br
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Boc-NH-C4-Br图片
CAS NO:164365-88-2
包装与价格：
包装价格(元)
50mg电议
100mg电议

产品介绍
Boc-NH-C4-Br 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。
Cas No.164365-88-2
别名叔丁基N-(4-溴丁基)氨基甲酸
分子式C9H18BrNO2
分子量252.15
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Hu R, et, al. Identification of a selective BRD4 PROTAC with potent antiproliferative effects in AR-positive prostate cancer based on a dual BET/PLK1 inhibitor. Eur J Med Chem. 2022 Jan 5;227:113922.