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PPTN
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PPTN图片
CAS NO:1160271-30-6
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品介绍
PPTN 是一种有效,高亲和力,竞争性和高选择性的 P2Y14 受体拮抗剂,KB 为 434 pM。PPTN 对 P2Y1,P2Y2,P2Y4,P2Y6,P2Y11,P2Y12 或 P2Y13 受体无激动剂或拮抗剂作用。具有抗炎和免疫活性。

产品描述

PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.

体外活性

PPTN exhibits strong selectivity for the P2Y14-R over the other seven nucleotide-activated P2Y receptors. PPTN inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM in the presence of 10 μM UDP-glucose and ~4 nM in the presence of 100 μM[1].

Cas No.

1160271-30-6

分子式

C29H24F3NO2

分子量

475.5

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years