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Prasugrel hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prasugrel hydrochloride图片
CAS NO:389574-19-0
包装与价格:
包装价格(元)
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Prasugrel HCl
PCR 4099 (hydrochloride)
盐酸普拉格雷
Effient Hydrochloride
LY 640315 Hydrochloride
LY 640315
产品介绍
PRasugrel hydrochloride 是一种噻吩吡啶和前药,是一种可口服的P2Y12受体拮抗剂,抑制 ADP 诱导的血小板聚集,用于预防急性冠状动脉综合征患者的血栓形成、不稳定型心绞痛和心肌梗塞,以及接受经皮冠状动脉介入治疗的患者。

产品描述

Prasugrel hydrochloride is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

体内活性

Prasugrel significantly inhibits arterio-venous (AV) shunt and electrically induced arterial thrombosis in single dose ranges of 0.3 to 3 mg/kg and of 0.3 and 1 mg/kg/day for multiple doses. These doses are similar to doses with inhibition of platelet activation via P2Y12 receptors, suggesting that the protective effects of prasugrel in these cerebral infarction and peripheral arterial occlusive disease models reflect P2Y12 inhibitions on platelets by prasugrel's active metabolite. Prasugrel also significantly prevents progression of peripheral vascular lesions[1].

Cas No.

389574-19-0

分子式

C20H21ClFNO3S

分子量

409.9

别名

Prasugrel HCl;PCR 4099 (hydrochloride);盐酸普拉格雷;Effient Hydrochloride;LY 640315 Hydrochloride;LY 640315

储存和溶解度

Ethanol:9 mg/mL (21.95 mM)
H2O:<1 mgml
DMSO:43 mg/mL (104.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years