Praeruptorin A 是一种白花前胡的主要生物活性成分。它能够抑制NF-Κb活化,发挥抗炎作用。
产品描述
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
Cas No.
73069-27-9
分子式
C21H22O7
分子量
386.4
别名
白花前胡甲素;(+)-Praeruptorin A
储存和溶解度
DMSO:199.3 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years