CAS NO: | 2357108-99-5 |
包装: | 50mg |
市场价: | 13950元 |
Cas No. | 2357108-99-5 |
分子式 | C12H22N4O2 |
分子量 | 254.33 |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 [1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1. |