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2-Chloro-N6-cyclopentyladenosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Chloro-N6-cyclopentyladenosine图片
CAS NO:37739-05-2
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议

产品名称
2-CHLORO-N-CYCLOPENTYLADENOSINE
2-氯-N6-环戊基腺苷
CCPA
2-chloro-N(6)cyclopentyladenosine
产品介绍
2-Chloro-N6-cyclopentyladeNOSine 是一种有效的选择性腺苷 A1 受体激动剂。

产品描述

2-Chloro-N6-cyclopentyladenosine is a potent and selective agonist of adenosine A1 receptor

体外活性

2-Chloro-N6-cyclopentyladenosine suppressed the mRNA and protein expressions of CnAβ and exerted antihypertrophic effects to a greater degree than CsA. The inhibition of 2-Chloro-N6-cyclopentyladenosine on cardiomyocyte hypertrophy was counteracted by the A1 receptor antagonist DPCPX[1].

体内活性

2-Chloro-N6-cyclopentyladenosine (CCPA) was synthesized as a potential high affinity ligand for A1 adenosine receptors. Binding of [3H]PIA to A1 receptors of rat brain membranes was inhibited by CCPA with a Ki-value of 0.4 nM, compared to a Ki-value of 0.8 nM for the parent compound N6-cyclopentyladenosine (CPA)[2].

Cas No.

37739-05-2

分子式

C15H20ClN5O4

分子量

369.81

别名

2-CHLORO-N-CYCLOPENTYLADENOSINE;2-氯-N6-环戊基腺苷;CCPA;2-chloro-N(6)cyclopentyladenosine

储存和溶解度

DMSO:55 mg/ml (148.73 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years