您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Levonorgestrel-D8
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Levonorgestrel-D8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Levonorgestrel-D8图片
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Levonorgestrel-D8 (D-Norgestrel-D8) 是 Levonorgestrel 的氘代物。Levonorgestrel是合成孕激素,可作用于孕酮受体。
别名D-Norgestrel-D8
分子式C21H20D8O2
分子量320.5
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Levonorgestrel-D8 (D-Norgestrel-D8) is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Gallos, I.D., et al., Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis. Am J Obstet Gynecol, 2010. 203(6): p. 547 e1-10.