PRN1008 是一种可逆的、选择性的、有口服活性的布鲁顿氏酪氨酸激酶(BTK)共价抑制剂，其IC50=1.3 nM。

PRN1008 is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK)(IC50 of 1.3 nM).

1575596-29-0

C36H40FN9O3

665.76

PRN1008

DMSO:130 mg/mL (195.27 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years