CAS NO: | 651042-82-9 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
Cas No. | 651042-82-9 |
别名 | 2,5,8,11,14,17,20-七氧杂二十二烷-22-硫醇 |
分子式 | C15H32O7S |
分子量 | 356.48 |
溶解度 | DMSO : 100 mg/mL (280.52 mM; Need ultrasonic) |
储存条件 | 4°C, protect from light, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | m-PEG7-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |