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Mal-NH-ethyl-SS-propionic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mal-NH-ethyl-SS-propionic acid图片
CAS NO:2128735-24-8
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Mal-NH-ethyl-SS-propionic acid 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
Cas No.2128735-24-8
分子式C12H16N2O5S2
分子量332.4
溶解度DMSO : 100 mg/mL (300.84 mM; Need ultrasonic)
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mal-NH-ethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.