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Tesirine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tesirine图片
CAS NO:1595275-62-9
包装:1mg
市场价:17280元

产品介绍
Tesirine (SG3249) 是一种用于抗体偶联药物 (ADC) 的 药物-linker 连接物,能用于多种癌症的研究。PBD Dimer 是一种 DNA 烷化剂,能抑制 DNA 复制。
Cas No.1595275-62-9
别名SG3249
分子式C75H101N9O23
分子量1496.65
溶解度DMSO : 200 mg/mL (133.63 mM; Need ultrasonic)
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tesirine (SG3249) is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].

[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs. Uppsala Universitet.