SeclidemSTAT 是非竞争性可逆KDM1A (LSD1)抑制剂，可用于尤文肉瘤的研究。它促进 SWI/SNF 复合物突变卵巢癌的抗肿瘤免疫，并抑制病毒产生、病毒 DNA 复制和晚期基因表达。

Seclidemstat is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.

Interstitial MR lymphography with gadopentetate dimeglumine (Gd-DTPA) allows clear visualization of the lymphatic pathway in healthy mice, and no significant difference is found between the two agents. Their rapid kinetics limits the imaging timing window, however, facilitates repeated assessment in a single imaging session [1]. Direct visualization of spilled gastrointestinal gadopentetate dimeglumine helps discriminate ischemic from control rats in this model [2].

1423715-37-0

C20H23ClN4O4S

450.94

SP-2577

DMSO:100 mg/mL (221.76 mM),Need ultrasonic
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years