Amifostine trihydrate 是一种广谱细胞保护剂和辐射防护剂。它可选择性保护正常组织免受放射线和化学疗法造成的损害。它是有效的HIF-α1和p53诱导剂。它通过清除氧衍生的自由基来保护细胞免受损伤。它可降低肾脏毒性并具有抗血管生成作用。

Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.

112901-68-5

C5H21N2O6PS

268.26

Ethyol trihydrate;三水氨磷汀;Amifostine;WR2721

H2O:10 mM
DMSO:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years