| CAS NO: | 1866-15-5 |
| 包装 | 价格(元) |
| 5 g | 电议 |
| 10 g | 电议 |
| 25 g | 电议 |
| 50 g | 电议 |
| Cas No. | 1866-15-5 |
| 别名 | 碘代硫代乙酰胆碱 |
| Canonical SMILES | O=C(C)SCC[N+](C)(C)C.[I-] |
| 分子式 | C7H16NOS·I |
| 分子量 | 289.2 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Acetylthiocholine is a substrate for acetylcholinesterase (AChE) and an agonist of α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs).1,2It binds to α4β2 subunit-containing nAChRs in SH-EP1 cells (IC50= 7.1 µM for the human receptor) and induces rubidium efflux in an agonist-induced rubidium efflux assay (EC50= 100 µM).2Acetylthiocholine has been used as part of a thiocholine sensor for the detection of pesticides in complex sample types, such as soil, groundwater, and spinach.1 1.Chen, L., Tian, X., Li, Y., et al.Broad-spectrum pesticide screening by multiple cholinesterases and thiocholine sensors assembled high-throughput optical array systemJ. Hazard. Mater.402123830(2021) 2.Eaton, J.B., Peng, J.-H., Schroeder, K.M., et al.Characterization of human α4β2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cellsMol. Pharmacol.64(6)1283-1294(2003) |
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