| CAS NO: | 88069-49-2 |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| Cas No. | 88069-49-2 |
| 别名 | 盐酸吡西卡呢,SUN-1165; Pilzicainide(hydrochloride) |
| Canonical SMILES | O=C(CC12N(CCC2)CCC1)NC3=C(C)C=CC=C3C.Cl |
| 分子式 | C17H24N2O·HCl |
| 分子量 | 308.9 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 25 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pilsicainide is a class Ic antiarrhythmic agent.1,2It shortens action potential duration in canine Purkinje fibers, as well as increases the ratio of the effective refractory period to the duration of action potential in guinea pig atrial muscle strips, when used at a concentration of 10 µg/ml.1Pilsicainide (3-10 mg/kg) restores sinus rhythm in a canine model of ventricular multifocal arrhythmias.2It also suppresses arrhythmias induced by ouabain or halothane and epinephrine in dogs. Formulations containing pilsicainide have been used in the treatment of supraventricular and ventricular tachycardia. 1.Hattori, Y., Inomata, N., Aisaka, K., et al.Electrophysiological actions of N-(2,6-dimethylphenyl)-8-pyrrolizidine-acetamide hydrochloride hemihydrate (SUN 1165), a new antiarrhythmic agentJ. Cardiovasc. Pharmacol.8(5)998-1002(1986) 2.Aisaka, K., Hidaka, T., Inomata, N., et al.N-(2,6-Dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate (SUN 1165): A new potent and long-acting antiarrhythmic agentArzneimittelforschung35(8)1239-1245(1985) |
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