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BnO-PEG4-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BnO-PEG4-OH图片
CAS NO:86259-87-2
包装:100mg
市场价:810元

产品介绍
BnO-PEG4-OH 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.86259-87-2
别名四甘醇单苄醚
分子式C15H24O5
分子量284.35
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.