CAS NO: | 211859-73-3 |
包装: | 50mg |
市场价: | 720元 |
Cas No. | 211859-73-3 |
别名 | 2,5,8,11,14,17,20,23,26-九氧杂二十八烷-28-胺 |
分子式 | C19H41NO9 |
分子量 | 427.53 |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | m-PEG9-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Xuyuan Gu, et al. Oligomer-Amino Acid Conjugates. US20120053237A1. |