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MMAE-SMCC
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MMAE-SMCC图片
CAS NO:2021179-11-1
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
MMAE-SMCC 是由有效的有丝分裂和微管蛋白抑制剂 MMAE 和接头 SMCC 组成的抗体偶联药物,可制成抗体药物偶联物。
Cas No.2021179-11-1
分子式C58H89N7O14S
分子量1140.43
溶解度DMSO : 220 mg/mL (192.91 mM; Need ultrasonic)
储存条件Store at -20°C,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].

[1]. Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518.