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CBP/p300 ligand 2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CBP/p300 ligand 2图片
CAS NO:2484741-78-6
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
CBP/p300 ligand 2 是 dCBP-1 的 PROTAC 靶蛋白的配体。dCBP-1 是一种有效且选择性的 p300/CBP 异双功能降解剂。
Cas No.2484741-78-6
分子式C27H34F2N8O
分子量524.61
溶解度DMSO : 200 mg/mL (381.24 mM; Need ultrasonic)
储存条件4°C, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

CBP/p300 ligand 2 (example 229) has no toxicity to LNCaP prostate cancer cells[1].

[1]. Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. O2020173440A1.