MAK683 是胚胎外胚层发育 (EED) 抑制剂，详细信息来自专利US20160176882 A1，化合物实例 2。在 EED Alphascreen 结合、LC-MS 和 ELISA 测定中，IC50值为 59、89 和 26 nM。

MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).

After treatment 14 days, MAK683 has antiproliferative activities in B cell lymphoma cell KARPAS422 (IC50: 30 nM) [1].

1951408-58-4

C20H17FN6O

376.39

DMSO:50 mg/mL (132.84 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years