CAS NO: | 2412056-48-3 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
Cas No. | 2412056-48-3 |
分子式 | C24H31N3O10 |
分子量 | 521.52 |
溶解度 | DMSO : 80 mg/mL (153.40 mM; Need ultrasonic) |
储存条件 | 4°C, away from moisture and light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1]. Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1[1]. [1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4. |