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Amino-PEG2-NH-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amino-PEG2-NH-Boc图片
CAS NO:127828-22-2
包装:100mg
市场价:1080元

产品介绍
Amino-PEG2-NH-Boc 是基于 PEG 的 PROTAC linker,用于合成 PROTAC。
Cas No.127828-22-2
别名[2-(2-氨基乙氧基)乙基]氨基甲酸叔丁酯
分子式C9H20N2O3
分子量204.27
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Qiu X, et al. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019 May 17;21(10):3838-3841.