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(S,R,S)-AHPC-PEG5-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(S,R,S)-AHPC-PEG5-Boc图片
包装与价格:
包装价格(元)
100mg电议
250mg电议

产品介绍
(S,R,S)-AHPC-PEG5-Boc是一种E3连接酶配体-linker偶联物(E3ligaseligand-linkerconjugate),包含基于(S,R,S)-AHPC的VHL配体和1个linker。用于合成Cdc20降解剂CP5V。
Canonical SMILESCC(C)(C)[C@@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)NC(CCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O
分子式C40H62N4O11S
分子量807.01
储存条件-20℃, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V[1].

[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.