RHC 80267 是一种选择性二酰基甘油脂酶(DAGL)抑制剂，对犬血小板的IC50为 4 μM。它抑制COX活性和磷脂酰胆碱的水解，还抑制胆碱酯酶活性，IC50为 4 μM，增强乙酰胆碱引起的松弛。

RHC 80267 is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)

RHC-80267 is thought to initiate activation of protein kinase C.2?At 0.3-1 μM, it has been reported to enhance acetylcholine-induced smooth muscle relaxation?in vitro

83654-05-1

C20H34N4O4

394.516

U-57908

DMSO:25 mg/mL (63.37 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years