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Miglustat hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Miglustat hydrochloride图片
CAS NO:210110-90-0
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
盐酸美格鲁特
NB-DNJ hydrochloride
OGT918 hydrochloride
N-Butyldeoxynojirimycin hydrochloride
产品介绍
MigluSTAT hydrochloride 是一种葡萄糖神经酰胺合酶抑制剂,可用于 I 型戈谢病的相关研究。

产品描述

Miglustat hydrochloride is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.

体内活性

Consumption of a standard high-fat breakfast within 30 minutes before administration of Miglustat hydrochloride significantly reduced peak exposure but did not significantly affect the extent of systemic exposure to Miglustat hydrochloride. The Cmax decreased by 36% on average following administration with food. AUC showed a modest (14%) decrease with food, but the 90% confidence interval was within the acceptance limit of 80% to 125%. Tmax was prolonged from 2.5 (1.0-4.0) hours in the fasted state to 4.5 (1.5-8.0) hours in the fed state, whereas the apparent terminal half-life was approximately 8 hours and not affected by food[1].

Cas No.

210110-90-0

分子式

C10H22ClNO4

分子量

255.74

别名

盐酸美格鲁特;NB-DNJ hydrochloride;OGT918 hydrochloride;N-Butyldeoxynojirimycin hydrochloride

储存和溶解度

H2O:32 mg/mL (125.13 mM)
DMSO:60 mg/mL (234.61 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years