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3'-Demethylnobiletin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3'-Demethylnobiletin图片
CAS NO:112448-39-2
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物,是一种 Nobiletin 的衍生物。N其中obiletin 能够调节 Src,FAK 和 STAT3 信号传导来抗肿瘤,并能够抑制肿瘤血管生成。

产品描述

3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human colon cancer cells, cause cell-cycle arrest, induce apoptosis, and profoundly modulate signaling proteins related with cell proliferation and cell death.

体外活性

3'-Demethylnobiletin significantly suppressed CD36 expression. The inhibitory effects of 3'-Demethylnobiletin toward TPA-induced SR mRNA expression are partly associated with the suppression of AP-1 and NF-κB transcriptional activities[1].

Cas No.

112448-39-2

分子式

C20H20O8

分子量

388.37

储存和溶解度

DMSO:80 mg/mL (206 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years