MK-0941 free base 是一种口服具有活力的葡糖激酶抑制剂，在葡萄糖浓度为 2.5 和 10 mM 的条件下，对重组人 Glucokinase 的EC50值分别为 240 和 65 nM。它具有较强的降血糖特性，是研究 2 型糖尿病的候选药物。

MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.

MK-0941 free base treatment reduced blood glucose significantly in db/db diabetic mouse[1].

752240-01-0

C21H24N4O6S

460.5

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years