ML266 是葡萄糖脑苷脂酶 (GCase) 分子伴侣， IC50值为 2.5 μM。ML266与 GCase 结合并将其转运至溶酶体，恢复 GCase 酶的活性。ML266 不会抑制 GCase 的活性。ML266 具有研究戈谢病的潜力。

ML266 is glucocerebrosidase (GCase) molecule chaperone, IC50 = 2.5 μM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease.

1462267-08-8

C24H22BrN3O4

496.35

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years