ML198 是葡萄糖脑苷脂酶激活剂(EC50:0.4 μM)。它不会抑制该酶的作用,且能促进其易位至溶酶体,可用于研究戈谢病。
产品描述
ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease.
Cas No.
1380716-06-2
分子式
C17H14N4O
分子量
290.326
储存和溶解度
H2O:Insoluble
DMSO:2.9 mg/ml (10 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years