Homovanillyl alcohol 是羟基酪醇的生物代谢物。HydroxytyROSol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤,并对心血管具有保护作用。
产品描述
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol displays high scavenging activities, it protects red blood cells from hemolysis in a dose-dependent manner. Homovanillyl alcohol has protective effect on cardiovascular disease and total mortality.
体外活性
Structurally related compounds have been assayed for their ability to reduce homocysteine-induced monocyte adhesion as well as the cell surface expression of intercellular adhesion molecule-1 (ICAM-1) in EA.hy.926 cells. As well-known, among the selected phenolic compounds, hydroxytyrosol, Homovanillyl alcohol, and the hydroxycinnamic acid derivatives caffeic and ferulic acid display high scavenging activities, while tyrosol and p-coumaric acid are poorly active. All of the tested compounds, approaching potential in vivo concentrations, significantly reduce homocysteine-induced cell adhesion and ICAM-1 expression.
Cas No.
2380-78-1
分子式
C9H12O3
分子量
168.19
别名
4-羟基-3-甲氧基苯乙醇;高香草醇
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years