GSK2981278 是RORγ的选择性反向激动剂。它能够抑制il17启动子的激活,并且干扰 RORγ-DNA 结合。
产品描述
GSK2981278 is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
Cas No.
1474110-21-8
分子式
C25H35NO5S
分子量
461.62
别名
ROR gama modulator 1
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years