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(-)-Epigallocatechin Gallate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-Epigallocatechin Gallate图片
CAS NO:989-51-5
包装与价格:
包装价格(元)
50 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
EGCG
Epigallocatechol Gallate
(-)-表没食子儿茶素没食子酸酯
产品介绍
(-)-EpigalloCATechin Gallate是茶类黄酮,具有强大的抗氧化,抗炎和抗癌作用。它可抑制EGFR信号传导,有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c氧化酶来诱导氧化磷酸化。

产品描述

Epigallocatechol Gallate(EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. EGCG is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells.

体内活性

Epigallocatechol Gallate (5 and 20 mg/kg, p.o.) inhibits the growth of tumor in the subcutaneous orthotopic transplant model[4].

细胞实验

LoVo, SW480, HCT-8, and HT-29 cells are seeded in 96-well plates at a concentration of 5×103?cells; each cell line is totally seeded in the 12 wells. Complete medium is added to the wells, up to 200 μL; the medium contains 0 μg/mL, 10 μg/mL, 20 μg/mL, and 35 μg/mL of epigallocatechol gallate. The inhibition rate=[1 - (absorbance of Epigallocatechol Gallate group - absorbance of control group)/(absorbance of control group - absorbance of blank control group)] × 100.

Cas No.

989-51-5

分子式

C22H18O11

分子量

458.375

别名

EGCG;Epigallocatechol Gallate;(-)-表没食子儿茶素没食子酸酯

储存和溶解度

H2O:4.6 mg/mL (10 mM)
Ethanol:45.8 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years