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4,4-Dimethyl-2-cyclopenten-1-one
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4,4-Dimethyl-2-cyclopenten-1-one图片
CAS NO:22748-16-9
包装:10mg
市场价:450元

产品介绍
4,4-Dimethyl-2-cyclopenten-1-one是可来源于ApocynivenetiFolium的天然产物,对不同肿瘤细胞显示出高选择性的细胞毒性。
Cas No.22748-16-9
别名4,4-二甲基-2-环戊烯-1-酮,4,4-Dimethylcyclopent-2-enone
Canonical SMILESO=C1C=CC(C)(C)C1
分子式C7H10O
分子量110.15
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity[1].

4,4-Dimethyl-2-cyclopenten-1-one selectively kills the tumor cells (HSC-2, HL-60). 4,4-Dimethyl-2-cyclopenten-1-one exhibits CC50 (50% cytotoxic concentration) values of 43.8 μg/mL, 152 μg/mL, 118 μg/mL, 14.0 μg/mL, 177 μg/mL and 123 μg/mL in HSC-2, HSC-3, HSG, HL-60, HGF and normal cells (HPC), respectively[1].

[1]. Tohru Nakayachi, et al. Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells. Anticancer Res. Mar-Apr 2004;24(2B):737-42. [2]. Wei-WeiZhu, et al. Cornstalk liquefaction in methanol/water mixed solvents. Fuel Processing Technology Volume 117, January 2014, Pages 1-7.