| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Canonical SMILES | CC1=NN=C(C2=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCC(N3C4=CC=CC=C4C#CC5=CC=CC=C5C3)=O)=O)C=C2)N=N1 |
| 分子式 | C52H70N6O14 |
| 分子量 | 1003.14 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Methyltetrazine-PEG12-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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