ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 Ras 癌基因的细胞系。

ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)

1035072-16-2

C23H22Cl2N2O3S

477.4

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years