AZD 3241 是一种不可逆的、选择性的、口服具有活力的髓过氧化物酶 (myeloperoxidase) 抑制剂,IC50=630 nM,可用于研究大脑神经退行性疾病。
产品描述
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
体外活性
Verdiperstat (AZD3241) is a myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders[1]. Verdiperstat (AZD3241) selectively and irreversibly inhibits myeloperoxidase, and may involves reduction of oxidative stress leading to reduction of sustained neuroinflammation.
Cas No.
890655-80-8
分子式
C11H15N3O2S
分子量
253.32
别名
AZD3241;AZD 3241
储存和溶解度
DMSO:150 mg/mL (592.14 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years