| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 别名 | Thiol-PEG3-amine hydrochloride |
| Canonical SMILES | NCCOCCOCCOCCS.[H]Cl |
| 分子式 | C8H20ClNO3S |
| 分子量 | 245.77 |
| 溶解度 | DMSO: 250 mg/mL (1017.21 mM) |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | HS-PEG3-CH2CH2NH2 hydrochloride (Thiol-PEG3-amine hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
m.cnreagent.com