| CAS NO: | 158913-22-5 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 158913-22-5 |
| 别名 | 琥珀酰亚胺基-6-[3-(2-吡啶基二硫基)丙酰胺基]己酸 |
| Canonical SMILES | O=C(CCCCCNC(CCSSC1=NC=CC=C1)=O)ON2C(CCC2=O)=O |
| 分子式 | C18H23N3O5S2 |
| 分子量 | 425.52 |
| 溶解度 | DMSO: 100 mg/mL (235.01 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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