Ibudilast 是一种环腺苷酸磷酸二酯酶 (PDE) 抑制剂，具有抗血小板聚集作用。它能够抑制气管平滑肌收缩性，可用于研究哮喘。它可对抗活化小胶质细胞的神经毒性，可能是一种有效的神经保护和抗痴呆药物。

Ibudilast(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.

50847-11-5

C14H18N2O

230.51

KC-404;异丁司特;MN-166;AV-411

Ethanol:23 mg/mL(100 mM)
DMSO:28 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years