Tauro-Obeticholic acid 是一种牛磺酸的特性代谢物。Obeticholic Acid 是口服具有活性的法尼样X受体激动剂。
产品描述
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
体外活性
Obeticholic acid and taurine are conjugated in the liver to form taurine-obeticholic acid, which is secreted into the bile. Microorganisms in the ileum and colon can dissociate taurine-cholesteric acid and convert it into the parent drug, which can then be reabsorbed or excreted in feces.
Cas No.
863239-61-6
分子式
C28H49NO6S
分子量
527.76
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years