DY-268 是一种法尼样X受体 (FXR)的拮抗剂(在 time-resolved FRET 分析中，IC50=7.5 nM)。在细胞分析中，它能够抑制 FXR 反式激活，IC50=468 nM。

DY-268 is a compound based on trisubstituted pyrazolamide without any FXR agonist activity and cytotoxicity and can be used as an effective FXR antagonist (IC50 = 7.5 nM).

1609564-75-1

C30H32N4O5S

560.66

DY-268;DY 268

DMSO:Soluble
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years