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Boc-C2-NH2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Boc-C2-NH2图片
CAS NO:15231-41-1
包装:250mg
市场价:495元

产品介绍
Boc-C2-NH2是一种PROTAClinker,属于alkyl/ether类。可用于合成PROTAC分子。
Cas No.15231-41-1
别名3-氨基丙酸叔丁酯
Canonical SMILESO=C(OC(C)(C)C)CCN
分子式C7H15NO2
分子量145.2
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Boc-C2-NH2 is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562