DDO-5936 是一种特异性HSP90-Cdc37 PPI抑制剂,可研究大肠癌。
产品描述
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
体外活性
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor through binding to a critical site on HSP90 involving Glu47.
体内活性
DDO-5936 is well tolerated for the absence of serious weight loss. DDO-5936 decreased tumor cells in the xenografts significantly in high dose group.
Cas No.
2355377-13-6
分子式
C25H29N5O4S
分子量
495.6
储存和溶解度
DMSO:6 mg/ml (12.11 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years