Demethylzeylasteral 是一种从雷公藤中分离出的三萜烯化合物,具有抗炎、免疫抑制和抗肿瘤活性。它通过阻断 TGF-β 信号通路,抑制三阴性乳腺癌的侵袭。它能显著减轻动脉粥样硬化。
产品描述
Demethylzeylasteral has strong immunosuppressive activity, can be used in the fields of organ transplantation and autoimmune disorders. The risk of elevated serum concentrations of estradiol due to the inhibition of estradiol glucuronidation by Demethylzeylasteral. Demethylzeylasteral increases both activation and inactivation time constants of Ca(2+) currents, can inhibit significantly the sperm acrosome reaction initiated by progesterone.
Cas No.
107316-88-1
分子式
C29H36O6
分子量
480.601
别名
去甲泽拉木醛;Demethylzeylasteral (T-96)
储存和溶解度
DMSO:87 mg/mL(181 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years