JZP-430 是不可逆的、高度选择性的 α/β 水解酶结构域 6 抑制剂，能够靶向抑制人类 ABHD6 ，其IC50=44 nM。
产品描述
JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
Cas No.
1672691-74-5
分子式
C16H26N4O3S
分子量
354.47
储存和溶解度
DMSO:90 mg/mL (253.9 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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